diff --git a/.examples/_config_example.yaml b/.examples/_config_example.yaml
index 29567c77..a1eee32f 100644
--- a/.examples/_config_example.yaml
+++ b/.examples/_config_example.yaml
@@ -77,4 +77,4 @@ utility_parameters:
   METABASE_MIN_MEMORY: "2g"
   METABASE_MAX_MEMORY: "8g"
   METABASE_VERSION: "v0.49.6"
-  METABASE_DUCKDB_PLUGIN_VERSION: "0.2.6"
+  METABASE_DUCKDB_PLUGIN_VERSION: "0.2.8"
diff --git a/workflow/Database b/workflow/Database
index fdfa84f9..5c5b985c 100644
--- a/workflow/Database
+++ b/workflow/Database
@@ -39,6 +39,7 @@ for name in PEP_PROJECTS.keys():
                 model_to_ignore.append(item)
     models_to_ignore[name] = model_to_ignore
     db.append(f"data/processed/{name}/dbt/antiSMASH_{version}/dbt_bgcflow.duckdb")
+    db.append(f"data/processed/{name}/antismash_database/antiSMASH_database_{version}")
 
 rule all:
     input:
@@ -46,3 +47,4 @@ rule all:
 
 ##### Modules #####
 include: "rules/build-database.smk"
+include: "rules/antismash-db-duckdb.smk"
diff --git a/workflow/Metabase b/workflow/Metabase
index 58e247a9..89767c76 100644
--- a/workflow/Metabase
+++ b/workflow/Metabase
@@ -157,7 +157,7 @@ metabase_config = {
     "METABASE_MIN_MEMORY": "2g",
     "METABASE_MAX_MEMORY": "8g",
     "METABASE_VERSION": "v0.49.6",
-    "METABASE_DUCKDB_PLUGIN_VERSION": "0.2.6",
+    "METABASE_DUCKDB_PLUGIN_VERSION": "0.2.8",
     "DMB_SETUP_TOKEN": "ad0fb086-351b-4fa5-a17e-76282d2c9753",
     "METABASE_HTTP": "http://localhost:3000",
     "MB_IS_METABOT_ENABLED" : "true"
diff --git a/workflow/envs/antismash_db-duckdb.post-deploy.sh b/workflow/envs/antismash_db-duckdb.post-deploy.sh
new file mode 100644
index 00000000..d202efc9
--- /dev/null
+++ b/workflow/envs/antismash_db-duckdb.post-deploy.sh
@@ -0,0 +1,39 @@
+set -e
+
+# Create a directory for resources if it doesn't already exist
+mkdir -p resources
+rm -rf resources/antismash_db-schema_duckdb
+
+# create logs directory
+mkdir -p logs/antismash_db-duckdb
+LOG="logs/antismash_db-duckdb/antismash_db-duckdb_template.log"
+
+# Clone the antismash_db-schema_duckdb repository into the resources directory
+git clone https://github.com/NBChub/antismash_db-schema_duckdb.git resources/antismash_db-schema_duckdb 2>> $LOG
+
+# Clone the db-schema repository into the antismash_db-schema_duckdb directory
+git clone https://github.com/antismash/db-schema.git resources/antismash_db-schema_duckdb/db-schema 2>> $LOG
+
+# Download the antiSMASH databases using a custom script or command
+download-antismash-databases 2>> $LOG
+
+# Initialize the DuckDB database with the schema from the db-schema directory
+(cd resources/antismash_db-schema_duckdb && python init_duckdb.py db-schema duckdb-schema) 2>> $LOG
+
+# Download the NCBI taxonomy dump files into the ncbi-taxdump directory
+(cd resources/antismash_db-schema_duckdb && wget -P ncbi-taxdump https://ftp.ncbi.nlm.nih.gov/pub/taxonomy/new_taxdump/new_taxdump.tar.gz -nc) 2>> $LOG
+
+# Extract the downloaded NCBI taxonomy dump files
+(cd resources/antismash_db-schema_duckdb/ncbi-taxdump && tar -xvf new_taxdump.tar.gz) 2>> $LOG
+
+# Install the asdb-taxa tool using cargo (Rust's package manager)
+cargo install asdb-taxa 2>> $LOG
+
+# Add cargo's bin directory to the PATH to ensure asdb-taxa can be executed
+export PATH="$HOME/.cargo/bin:$PATH"
+
+# Clone the db-import repository into the antismash_db-schema_duckdb directory
+git clone git@github.com:matinnuhamunada/db-import.git resources/antismash_db-schema_duckdb/db-import 2>> $LOG
+
+# Checkout a specific branch of the db-import repository
+(cd resources/antismash_db-schema_duckdb/db-import && git checkout -b v4.0.0-duckdb v4.0.0-duckdb) 2>> $LOG
diff --git a/workflow/envs/antismash_db-duckdb.yaml b/workflow/envs/antismash_db-duckdb.yaml
new file mode 100644
index 00000000..38de4c9a
--- /dev/null
+++ b/workflow/envs/antismash_db-duckdb.yaml
@@ -0,0 +1,298 @@
+name: antismash_db_env
+channels:
+  - bioconda
+  - conda-forge
+dependencies:
+  - _libgcc_mutex=0.1=conda_forge
+  - _openmp_mutex=4.5=2_gnu
+  - anyio=4.2.0=pyhd8ed1ab_0
+  - argon2-cffi=23.1.0=pyhd8ed1ab_0
+  - argon2-cffi-bindings=21.2.0=py310h2372a71_4
+  - arrow=1.3.0=pyhd8ed1ab_0
+  - asttokens=2.4.1=pyhd8ed1ab_0
+  - async-lru=2.0.4=pyhd8ed1ab_0
+  - attrs=23.2.0=pyh71513ae_0
+  - babel=2.14.0=pyhd8ed1ab_0
+  - beautifulsoup4=4.12.3=pyha770c72_0
+  - binutils_impl_linux-64=2.40=hf600244_0
+  - blast=2.15.0=pl5321h6f7f691_1
+  - bleach=6.1.0=pyhd8ed1ab_0
+  - boost-cpp=1.74.0=h75c5d50_8
+  - brotli-python=1.1.0=py310hc6cd4ac_1
+  - bzip2=1.0.8=hd590300_5
+  - c-ares=1.26.0=hd590300_0
+  - ca-certificates=2024.2.2=hbcca054_0
+  - cached-property=1.5.2=hd8ed1ab_1
+  - cached_property=1.5.2=pyha770c72_1
+  - certifi=2024.2.2=pyhd8ed1ab_0
+  - cffi=1.16.0=py310h2fee648_0
+  - cfgv=3.3.1=pyhd8ed1ab_0
+  - charset-normalizer=3.3.2=pyhd8ed1ab_0
+  - comm=0.2.1=pyhd8ed1ab_0
+  - curl=8.5.0=hca28451_0
+  - debugpy=1.8.0=py310hc6cd4ac_1
+  - decorator=5.1.1=pyhd8ed1ab_0
+  - defusedxml=0.7.1=pyhd8ed1ab_0
+  - diamond=2.0.15=hb97b32f_1
+  - distlib=0.3.8=pyhd8ed1ab_0
+  - entrez-direct=16.2=he881be0_1
+  - entrypoints=0.4=pyhd8ed1ab_0
+  - exceptiongroup=1.2.0=pyhd8ed1ab_2
+  - executing=2.0.1=pyhd8ed1ab_0
+  - expat=2.5.0=hcb278e6_1
+  - fasttree=2.1.11=h031d066_2
+  - filelock=3.13.1=pyhd8ed1ab_0
+  - fqdn=1.5.1=pyhd8ed1ab_0
+  - gcc_impl_linux-64=13.2.0=h338b0a0_5
+  - gettext=0.21.1=h27087fc_0
+  - ghostscript=10.02.1=h59595ed_0
+  - glimmerhmm=3.0.4=pl5321h87f3376_5
+  - h11=0.14.0=pyhd8ed1ab_0
+  - h2=4.1.0=pyhd8ed1ab_0
+  - hmmer=3.4=hdbdd923_0
+  - hmmer2=2.3.2=h031d066_9
+  - hpack=4.0.0=pyh9f0ad1d_0
+  - httpcore=1.0.2=pyhd8ed1ab_0
+  - httpx=0.26.0=pyhd8ed1ab_0
+  - hyperframe=6.0.1=pyhd8ed1ab_0
+  - icu=70.1=h27087fc_0
+  - identify=2.5.33=pyhd8ed1ab_0
+  - idna=3.6=pyhd8ed1ab_0
+  - importlib-metadata=7.0.1=pyha770c72_0
+  - importlib_metadata=7.0.1=hd8ed1ab_0
+  - importlib_resources=6.1.1=pyhd8ed1ab_0
+  - ipykernel=6.29.0=pyhd33586a_0
+  - ipython=8.21.0=pyh707e725_0
+  - isoduration=20.11.0=pyhd8ed1ab_0
+  - jedi=0.19.1=pyhd8ed1ab_0
+  - json5=0.9.14=pyhd8ed1ab_0
+  - jsonpointer=2.4=py310hff52083_3
+  - jsonschema-specifications=2023.12.1=pyhd8ed1ab_0
+  - jsonschema-with-format-nongpl=4.21.1=pyhd8ed1ab_0
+  - jupyter-lsp=2.2.2=pyhd8ed1ab_0
+  - jupyter_client=8.6.0=pyhd8ed1ab_0
+  - jupyter_core=5.7.1=py310hff52083_0
+  - jupyter_events=0.9.0=pyhd8ed1ab_0
+  - jupyter_server=2.12.5=pyhd8ed1ab_0
+  - jupyter_server_terminals=0.5.2=pyhd8ed1ab_0
+  - jupyterlab=4.1.0=pyhd8ed1ab_0
+  - jupyterlab_pygments=0.3.0=pyhd8ed1ab_0
+  - jupyterlab_server=2.25.2=pyhd8ed1ab_0
+  - kernel-headers_linux-64=2.6.32=he073ed8_16
+  - keyutils=1.6.1=h166bdaf_0
+  - krb5=1.21.2=h659d440_0
+  - ld_impl_linux-64=2.40=h41732ed_0
+  - libcurl=8.5.0=hca28451_0
+  - libedit=3.1.20191231=he28a2e2_2
+  - libev=4.33=hd590300_2
+  - libexpat=2.5.0=hcb278e6_1
+  - libffi=3.4.2=h7f98852_5
+  - libgcc-devel_linux-64=13.2.0=ha9c7c90_105
+  - libgcc-ng=13.2.0=h807b86a_5
+  - libgomp=13.2.0=h807b86a_5
+  - libiconv=1.17=hd590300_2
+  - libidn2=2.3.7=hd590300_0
+  - libnghttp2=1.58.0=h47da74e_1
+  - libnsl=2.0.1=hd590300_0
+  - libsanitizer=13.2.0=h7e041cc_5
+  - libsodium=1.0.18=h36c2ea0_1
+  - libsqlite=3.44.2=h2797004_0
+  - libssh2=1.11.0=h0841786_0
+  - libstdcxx-ng=13.2.0=h7e041cc_5
+  - libunistring=0.9.10=h7f98852_0
+  - libuuid=2.38.1=h0b41bf4_0
+  - libxcrypt=4.4.36=hd590300_1
+  - libxml2=2.9.14=h22db469_4
+  - libxslt=1.1.35=h8affb1d_0
+  - libzlib=1.2.13=hd590300_5
+  - matplotlib-inline=0.1.6=pyhd8ed1ab_0
+  - meme=4.11.2=py310pl5321h2cd2fb3_8
+  - mistune=3.0.2=pyhd8ed1ab_0
+  - muscle=5.1=h4ac6f70_3
+  - nbclient=0.8.0=pyhd8ed1ab_0
+  - nbconvert-core=7.14.2=pyhd8ed1ab_0
+  - nbformat=5.9.2=pyhd8ed1ab_0
+  - ncbi-vdb=3.0.10=hdbdd923_0
+  - ncurses=6.4=h59595ed_2
+  - nest-asyncio=1.6.0=pyhd8ed1ab_0
+  - nodeenv=1.8.0=pyhd8ed1ab_0
+  - notebook-shim=0.2.3=pyhd8ed1ab_0
+  - openssl=3.2.1=hd590300_0
+  - ossuuid=1.6.2=hf484d3e_1000
+  - overrides=7.7.0=pyhd8ed1ab_0
+  - packaging=23.2=pyhd8ed1ab_0
+  - pandocfilters=1.5.0=pyhd8ed1ab_0
+  - parso=0.8.3=pyhd8ed1ab_0
+  - pcre=8.45=h9c3ff4c_0
+  - perl=5.32.1=7_hd590300_perl5
+  - perl-alien-build=2.48=pl5321hec16e2b_0
+  - perl-alien-libxml2=0.17=pl5321hec16e2b_0
+  - perl-archive-tar=2.40=pl5321hdfd78af_0
+  - perl-base=2.23=pl5321hd8ed1ab_0
+  - perl-business-isbn=3.007=pl5321hd8ed1ab_0
+  - perl-business-isbn-data=20210112.006=pl5321hd8ed1ab_0
+  - perl-capture-tiny=0.48=pl5321ha770c72_1
+  - perl-carp=1.50=pl5321hd8ed1ab_0
+  - perl-cgi=4.56=pl5321h031d066_1
+  - perl-common-sense=3.75=pl5321hd8ed1ab_0
+  - perl-compress-raw-bzip2=2.201=pl5321h166bdaf_0
+  - perl-compress-raw-zlib=2.202=pl5321h166bdaf_0
+  - perl-config-general=2.65=pl5321hdfd78af_0
+  - perl-constant=1.33=pl5321hd8ed1ab_0
+  - perl-dbi=1.643=pl5321h166bdaf_0
+  - perl-digest-md5=2.58=pl5321h166bdaf_0
+  - perl-encode=3.19=pl5321h166bdaf_0
+  - perl-encode-locale=1.05=pl5321hdfd78af_7
+  - perl-exporter=5.74=pl5321hd8ed1ab_0
+  - perl-exporter-tiny=1.002002=pl5321hd8ed1ab_0
+  - perl-extutils-makemaker=7.70=pl5321hd8ed1ab_0
+  - perl-ffi-checklib=0.28=pl5321hdfd78af_0
+  - perl-file-chdir=0.1011=pl5321hd8ed1ab_0
+  - perl-file-path=2.18=pl5321hd8ed1ab_0
+  - perl-file-spec=3.48_01=pl5321hdfd78af_2
+  - perl-file-temp=0.2304=pl5321hd8ed1ab_0
+  - perl-file-which=1.24=pl5321hd8ed1ab_0
+  - perl-html-parser=3.81=pl5321h4ac6f70_1
+  - perl-html-tagset=3.20=pl5321hdfd78af_4
+  - perl-html-template=2.97=pl5321hdfd78af_2
+  - perl-html-tree=5.07=pl5321hdfd78af_2
+  - perl-http-date=6.06=pl5321hdfd78af_0
+  - perl-http-message=6.36=pl5321hdfd78af_0
+  - perl-importer=0.026=pl5321hd8ed1ab_0
+  - perl-inc-latest=0.500=pl5321ha770c72_0
+  - perl-io-compress=2.201=pl5321hdbdd923_2
+  - perl-io-html=1.004=pl5321hdfd78af_0
+  - perl-io-zlib=1.14=pl5321hdfd78af_0
+  - perl-json=4.10=pl5321hdfd78af_0
+  - perl-json-xs=2.34=pl5321h4ac6f70_6
+  - perl-list-moreutils=0.430=pl5321hdfd78af_0
+  - perl-list-moreutils-xs=0.430=pl5321h031d066_2
+  - perl-log-log4perl=1.56=pl5321hd8ed1ab_0
+  - perl-lwp-mediatypes=6.04=pl5321hdfd78af_1
+  - perl-math-cdf=0.1=pl5321h031d066_9
+  - perl-mime-base64=3.16=pl5321h166bdaf_0
+  - perl-module-build=0.4234=pl5321ha770c72_0
+  - perl-parent=0.241=pl5321hd8ed1ab_0
+  - perl-path-tiny=0.124=pl5321hd8ed1ab_0
+  - perl-pathtools=3.75=pl5321h166bdaf_0
+  - perl-scalar-list-utils=1.63=pl5321h166bdaf_0
+  - perl-scope-guard=0.21=pl5321hd8ed1ab_0
+  - perl-storable=3.15=pl5321h166bdaf_0
+  - perl-sub-info=0.002=pl5321hd8ed1ab_0
+  - perl-sys-info=0.7811=pl5321hdfd78af_1
+  - perl-sys-info-base=0.7807=pl5321hdfd78af_1
+  - perl-sys-info-driver-linux=0.7905=pl5321hdfd78af_1
+  - perl-term-table=0.016=pl5321hdfd78af_0
+  - perl-test-fatal=0.016=pl5321ha770c72_0
+  - perl-test-nowarnings=1.06=pl5321ha770c72_0
+  - perl-test-warnings=0.031=pl5321ha770c72_0
+  - perl-test2-suite=0.000145=pl5321hdfd78af_0
+  - perl-text-template-simple=0.91=pl5321hdfd78af_1
+  - perl-time-local=1.35=pl5321hdfd78af_0
+  - perl-timedate=2.33=pl5321hdfd78af_2
+  - perl-try-tiny=0.31=pl5321ha770c72_0
+  - perl-types-serialiser=1.01=pl5321hdfd78af_0
+  - perl-unix-processors=2.046=pl5321h7f98852_1001
+  - perl-uri=5.17=pl5321ha770c72_0
+  - perl-url-encode=0.03=pl5321h9ee0642_0
+  - perl-xml-libxml=2.0207=pl5321h661654b_0
+  - perl-xml-namespacesupport=1.12=pl5321hd8ed1ab_0
+  - perl-xml-parser=2.44_01=pl5321hc3e0081_1003
+  - perl-xml-sax=1.02=pl5321hd8ed1ab_0
+  - perl-xml-sax-base=1.09=pl5321hd8ed1ab_0
+  - perl-xml-sax-expat=0.51=pl5321hd8ed1ab_0
+  - perl-xml-simple=2.25=pl5321hdfd78af_2
+  - perl-yaml=1.30=pl5321hdfd78af_0
+  - pexpect=4.9.0=pyhd8ed1ab_0
+  - pickleshare=0.7.5=py_1003
+  - pip=24.0=pyhd8ed1ab_0
+  - pkgutil-resolve-name=1.3.10=pyhd8ed1ab_1
+  - platformdirs=4.2.0=pyhd8ed1ab_0
+  - pre-commit=3.6.0=pyha770c72_0
+  - prodigal=2.6.3=h031d066_7
+  - prometheus_client=0.19.0=pyhd8ed1ab_0
+  - prompt-toolkit=3.0.42=pyha770c72_0
+  - psutil=5.9.8=py310h2372a71_0
+  - ptyprocess=0.7.0=pyhd3deb0d_0
+  - pure_eval=0.2.2=pyhd8ed1ab_0
+  - pycparser=2.21=pyhd8ed1ab_0
+  - pygments=2.17.2=pyhd8ed1ab_0
+  - pysocks=1.7.1=pyha2e5f31_6
+  - python=3.10.13=hd12c33a_1_cpython
+  - python-dateutil=2.8.2=pyhd8ed1ab_0
+  - python-fastjsonschema=2.19.1=pyhd8ed1ab_0
+  - python-json-logger=2.0.7=pyhd8ed1ab_0
+  - python_abi=3.10=4_cp310
+  - pytz=2024.1=pyhd8ed1ab_0
+  - pyyaml=6.0.1=py310h2372a71_1
+  - pyzmq=25.1.2=py310h795f18f_0
+  - readline=8.2=h8228510_1
+  - referencing=0.33.0=pyhd8ed1ab_0
+  - requests=2.31.0=pyhd8ed1ab_0
+  - rfc3339-validator=0.1.4=pyhd8ed1ab_0
+  - rfc3986-validator=0.1.1=pyh9f0ad1d_0
+  - rpds-py=0.17.1=py310hcb5633a_0
+  - rust=1.75.0=h70c747d_0
+  - rust-std-x86_64-unknown-linux-gnu=1.75.0=h2c6d0dc_0
+  - send2trash=1.8.2=pyh41d4057_0
+  - setuptools=69.0.3=pyhd8ed1ab_0
+  - six=1.16.0=pyh6c4a22f_0
+  - sniffio=1.3.0=pyhd8ed1ab_0
+  - soupsieve=2.5=pyhd8ed1ab_1
+  - stack_data=0.6.2=pyhd8ed1ab_0
+  - sysroot_linux-64=2.12=he073ed8_16
+  - terminado=0.18.0=pyh0d859eb_0
+  - tinycss2=1.2.1=pyhd8ed1ab_0
+  - tk=8.6.13=noxft_h4845f30_101
+  - tomli=2.0.1=pyhd8ed1ab_0
+  - tornado=6.3.3=py310h2372a71_1
+  - traitlets=5.14.1=pyhd8ed1ab_0
+  - types-python-dateutil=2.8.19.20240106=pyhd8ed1ab_0
+  - typing-extensions=4.9.0=hd8ed1ab_0
+  - typing_extensions=4.9.0=pyha770c72_0
+  - typing_utils=0.1.0=pyhd8ed1ab_0
+  - tzdata=2024a=h0c530f3_0
+  - ukkonen=1.0.1=py310hd41b1e2_4
+  - uri-template=1.3.0=pyhd8ed1ab_0
+  - urllib3=2.2.0=pyhd8ed1ab_0
+  - virtualenv=20.25.0=pyhd8ed1ab_0
+  - wcwidth=0.2.13=pyhd8ed1ab_0
+  - webcolors=1.13=pyhd8ed1ab_0
+  - webencodings=0.5.1=pyhd8ed1ab_2
+  - websocket-client=1.7.0=pyhd8ed1ab_0
+  - wget=1.20.3=ha35d2d1_1
+  - wheel=0.42.0=pyhd8ed1ab_0
+  - xz=5.2.6=h166bdaf_0
+  - yaml=0.2.5=h7f98852_2
+  - zeromq=4.3.5=h59595ed_0
+  - zipp=3.17.0=pyhd8ed1ab_0
+  - zlib=1.2.13=hd590300_5
+  - zstd=1.5.5=hfc55251_0
+  - pip:
+      - git+https://github.com/antismash/antismash.git@7-1-0-1
+      - bcbio-gff==0.7.0
+      - biopython==1.78
+      - brawn==1.0.1
+      - contourpy==1.2.1
+      - cycler==0.12.1
+      - duckdb==1.0.0
+      - fonttools==4.53.0
+      - helperlibs==0.2.1
+      - jinja2==3.1.2
+      - joblib==1.3.2
+      - jsonschema==4.11.0
+      - kiwisolver==1.4.5
+      - libsass==0.22.0
+      - markupsafe==2.1.3
+      - matplotlib==3.8.1
+      - moods-python==1.9.4.1
+      - nrpys==0.1.1
+      - numpy==1.26.2
+      - pillow==10.3.0
+      - pyparsing==3.1.2
+      - pyrsistent==0.20.0
+      - pysvg-py3==0.2.2.post3
+      - scikit-learn==1.3.2
+      - scipy==1.11.3
+      - threadpoolctl==3.5.0
+      - sqlparse==0.5.0
diff --git a/workflow/envs/bgcflow_notes.yaml b/workflow/envs/bgcflow_notes.yaml
index df342010..5cd9d87b 100644
--- a/workflow/envs/bgcflow_notes.yaml
+++ b/workflow/envs/bgcflow_notes.yaml
@@ -30,3 +30,4 @@ dependencies:
       - jupyterlab-dash
       - networkx
       - alive_progress
+      - duckdb==1.0.0
diff --git a/workflow/envs/dbt-duckdb.yaml b/workflow/envs/dbt-duckdb.yaml
index 4e717a54..fdeb800f 100644
--- a/workflow/envs/dbt-duckdb.yaml
+++ b/workflow/envs/dbt-duckdb.yaml
@@ -5,9 +5,9 @@ channels:
   - defaults
 dependencies:
   - python==3.11
-  - python-duckdb==0.9.2
+  - python-duckdb==1.0.0
   - unzip
   - pip
   - pip:
-    - dbt-duckdb==1.7.4
-    - dbt-metabase==1.3.0
+    - dbt-duckdb==1.8.1
+    - dbt-metabase==1.3.2
diff --git a/workflow/rules/antismash-db-duckdb.smk b/workflow/rules/antismash-db-duckdb.smk
new file mode 100644
index 00000000..69042608
--- /dev/null
+++ b/workflow/rules/antismash-db-duckdb.smk
@@ -0,0 +1,34 @@
+rule antismash_db_duckdb:
+    input:
+        antismash=lambda wildcards: expand("data/processed/{name}/antismash/{version}/{strains}",
+            name=wildcards.name,
+            version=wildcards.version,
+            strains=[s for s in PEP_PROJECTS[wildcards.name].sample_table.genome_id.unique()],
+        ),
+    output:
+        database=directory("data/processed/{name}/antismash_database/antiSMASH_database_{version}"),
+    conda:
+        "../envs/antismash_db-duckdb.yaml"
+    threads: 4
+    log:
+        "logs/antismash_db-duckdb/{name}_{version}.log",
+    params:
+        prefix=lambda wildcards: find_common_prefix(f"data/processed/{wildcards.name}/antismash/{wildcards.version}/"),
+        duckdb = "resources/antismash_db-schema_duckdb/duckdb-schema/antismash_db.duckdb",
+    shell:
+        """
+        set -e
+        mkdir -p {output.database}
+        bash_script=$PWD/resources/antismash_db-schema_duckdb/full_workflow.sh
+        input_dir=$PWD/data/processed/{wildcards.name}/antismash/{wildcards.version}
+
+        # Install the asdb-taxa tool using cargo (Rust's package manager)
+        cargo install asdb-taxa &>> {log}
+
+        # Add cargo's bin directory to the PATH to ensure asdb-taxa can be executed
+        export PATH="$HOME/.cargo/bin:$PATH"
+
+        # Run the full_workflow.sh script
+        duckdb=$PWD/{params.duckdb}
+        (cd {output.database} && bash $bash_script -p {params.prefix} $input_dir -d $duckdb) &>> {log}
+        """
diff --git a/workflow/rules/build-database.smk b/workflow/rules/build-database.smk
index 6932a688..59751e12 100644
--- a/workflow/rules/build-database.smk
+++ b/workflow/rules/build-database.smk
@@ -151,6 +151,7 @@ def exclude_model_dbt(model_to_ignore):
 
 rule build_database:
     input:
+        database="data/processed/{name}/antismash_database/antiSMASH_database_{version}",
         profile = "data/processed/{name}/dbt/antiSMASH_{version}/models/sources.yml"
     output:
         duckdb = "data/processed/{name}/dbt/antiSMASH_{version}/dbt_bgcflow.duckdb"
@@ -163,6 +164,7 @@ rule build_database:
         exclude = lambda wildcards: exclude_model_dbt(models_to_ignore[wildcards.name])
     shell:
         """
+        cp {input.database}/antismash_db.duckdb {output.duckdb} 2>> {log}
         command="dbt build --threads {threads} {params.exclude} -x"
         echo $command >> {log}
         (cd {params.dbt} \
diff --git a/workflow/rules/common.smk b/workflow/rules/common.smk
index 9a24c3d4..26644a7c 100644
--- a/workflow/rules/common.smk
+++ b/workflow/rules/common.smk
@@ -2,6 +2,7 @@ import os
 import numpy as np
 import pandas as pd
 import yaml, json, sys, itertools, hashlib
+from collections import defaultdict
 from snakemake.utils import validate
 from snakemake.utils import min_version
 from pathlib import Path
@@ -959,3 +960,30 @@ def get_user_input_with_timeout(prompt, timeout):
         result[0] = None  # Timeout occurred
 
     return result[0]
+
+def find_common_prefix(input_dir):
+    """
+    Find common prefixes of antiSMASH JSON files in the input directory.
+    Used in to define allowed prefixes in antismash-db-duckdb.smk
+    """
+    input_path = Path(input_dir)
+
+    # Find all .json files in the input directory recursively
+    json_files = list(input_path.glob('**/*.json'))
+
+    # Group files by the first letter of each file
+    files_by_first_letter = defaultdict(list)
+    for file in json_files:
+        first_letter = file.stem[0] if file.stem else ''
+        files_by_first_letter[first_letter].append(file)
+
+    # Find the common prefix within each group
+    common_prefixes = []
+    for files in files_by_first_letter.values():
+        filenames = [file.stem for file in files]
+        common_prefix = os.path.commonprefix(filenames)
+        if common_prefix:  # Only add non-empty prefixes
+            common_prefixes.append(common_prefix)
+
+    # Join the common prefixes with ","
+    return ",".join(common_prefixes)
diff --git a/workflow/rules/metabase.smk b/workflow/rules/metabase.smk
index 9a5c4d9a..12d447fd 100644
--- a/workflow/rules/metabase.smk
+++ b/workflow/rules/metabase.smk
@@ -23,5 +23,5 @@ rule metabase_duckdb_plugin:
         release=metabase_config["METABASE_DUCKDB_PLUGIN_VERSION"]
     shell:
         """
-        wget -O {output.plugin} https://github.com/AlexR2D2/metabase_duckdb_driver/releases/download/{params.release}/duckdb.metabase-driver.jar 2>> {log}
+        wget -O {output.plugin} https://github.com/MotherDuck-Open-Source/metabase_duckdb_driver/releases/download/{params.release}/duckdb.metabase-driver.jar 2>> {log}
         """