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error running nirvana " System.Runtime.InteropServices.SEHException (0x80004005): External component has thrown an exception." #96

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anapg11 opened this issue Feb 15, 2023 · 0 comments

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@anapg11
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anapg11 commented Feb 15, 2023

I use .NET 6.0 SDK (v6.0.406) and I have installed the latest version of Nirvana.

When I run the command "dotnet bin/Release/net6.0/Nirvana.dll  -c Data/Cache/GRCh37/Both  --sd Data/SupplementaryAnnotation/GRCh37  -r Data/References/Homo_sapiens.GRCh37.Nirvana.dat  -i HiSeq.10000.vcf.gz  -o HiSeq.10000"

The following error appears:

"Fatal error. System.Runtime.InteropServices.SEHException (0x80004005): External component has thrown an exception.
Repeat 2 times:

   at Compression.Algorithms.Zstandard+SafeNativeMethods.ZSTD_decompress(Byte[], UInt64, Byte[], UInt64)

   at Compression.Algorithms.Zstandard.Decompress(Byte[], Int32, Byte[], Int32)
   at Compression.DataStructures.Block.ReadCompressedBlock(System.IO.Stream)
   at Compression.DataStructures.Block.Read(System.IO.Stream)
   at Compression.FileHandling.BlockStream.Read(Byte[], Int32, Int32)
   at IO.BufferedBinaryReader.FillBuffer()
   at IO.BufferedBinaryReader..ctor(System.IO.Stream, Boolean, Int32)
   at VariantAnnotation.IO.Caches.TranscriptCacheReader..ctor(System.IO.Stream)
   at VariantAnnotation.Providers.TranscriptAnnotationProvider.InitiateCache(System.IO.Stream, System.Collections.Generic.Dictionary2<UInt16,Genome.Chromosome>, Genome.GenomeAssembly)    at VariantAnnotation.Providers.TranscriptAnnotationProvider..ctor(System.String, VariantAnnotation.Interface.Providers.ISequenceProvider, VariantAnnotation.Providers.ProteinConservationProvider)    at Nirvana.ProviderUtilities.GetTranscriptAnnotationProvider(System.String, VariantAnnotation.Interface.Providers.ISequenceProvider, VariantAnnotation.Providers.ProteinConservationProvider)    at Nirvana.AnnotationResources..ctor(System.String, System.String, System.Collections.Generic.List1<System.String>, System.Collections.Generic.List1<Cloud.Messages.SaUrls>, System.String, Boolean, Boolean, VariantAnnotation.PerformanceMetrics)    at Nirvana.Nirvana.GetAnnotationResources()    at Nirvana.Nirvana.ProgramExecution()    at CommandLine.Builders.ConsoleAppErrors.Execute(System.Func1<ErrorHandling.ExitCodes>)
   at Nirvana.Nirvana.Main(System.String[])
Illegal instruction "

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