diff --git a/lib/ddtrace/contrib/rails/core_extensions.rb b/lib/ddtrace/contrib/rails/core_extensions.rb
index 3c337a2dba..cd4839c018 100644
--- a/lib/ddtrace/contrib/rails/core_extensions.rb
+++ b/lib/ddtrace/contrib/rails/core_extensions.rb
@@ -336,7 +336,8 @@ def delete(*args, &block)
     end
 
     def self.reload_cache_store
-      return unless Datadog.registry[:redis].patched?
+      redis = Datadog.registry[:redis]
+      return unless redis && redis.patched?
 
       return unless defined?(::ActiveSupport::Cache::RedisStore) &&
                     defined?(::Rails.cache) &&