From 6ac72aaae166fbc603d2a8bd321fa30b6d1ead5f Mon Sep 17 00:00:00 2001
From: Alicen Henning <129797527+AlicenJoyHenning@users.noreply.github.com>
Date: Mon, 23 Sep 2024 11:01:55 +0200
Subject: [PATCH] Update README.md
---
README.md | 2 +-
1 file changed, 1 insertion(+), 1 deletion(-)
diff --git a/README.md b/README.md
index 94e2f7b..290722b 100644
--- a/README.md
+++ b/README.md
@@ -21,7 +21,7 @@ For droplet-based protocols, ‘low quality’ cells are those that originate fr
-```limiric``` is a quality control package that automates the sample-specific detection of damaged cells in one fast acting and highly reproducible function. It operates on the biological principle that damaged and healthy cells can be differentiated by the complexity of their mitochondrial and ribosomal gene expression, a complexity that can be effectively resolved through clustering in lower-dimensional space. Beyond predicting damaged cells, ```limiric``` offers functionality to estimate and correct for red blood cell contamination— an uncommon but significant artifact of single-cell isolation protocols for which no automated tool currently exists. If relevant to a user's investigation, ```limiric``` can also be used isolate immune (CD45^+) cell populations, a step performed prior to the detection and removal of damaged cells.
+```limiric``` is a quality control package that automates the sample-specific detection of damaged cells in one fast acting and highly reproducible function. It operates on the biological principle that damaged and healthy cells can be differentiated by the complexity of their mitochondrial and ribosomal gene expression, a complexity that can be effectively resolved through clustering in lower-dimensional space. Beyond predicting damaged cells, ```limiric``` offers functionality to estimate and correct for red blood cell contamination— an uncommon but significant artifact of single-cell isolation protocols for which no automated tool currently exists. If relevant to a user's investigation, ```limiric``` can also be used isolate immune (CD45⁺) populations, a step performed prior to the detection and removal of damaged cells.