diff --git a/CHANGELOG.md b/CHANGELOG.md
index daf32725f..4db3c7bd9 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -15,6 +15,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ### Fixed
 
+- issue with `trusted-replace-fetch-response` scriptlet in case if data URL was used and properties was set by
+  `Object.defineProperty` to deceive scriptlet [#367](https://github.com/AdguardTeam/Scriptlets/issues/367)
 - issue with adding the same header value in `trusted-replace-xhr-response` scriptlet
   when it is used multiple times for the same request [#359](https://github.com/AdguardTeam/Scriptlets/issues/359)
 - issue with not pruning in `m3u-prune` scriptlet if file contains carriage return
diff --git a/src/helpers/request-utils.ts b/src/helpers/request-utils.ts
index 644a6e9b4..946dbaeed 100644
--- a/src/helpers/request-utils.ts
+++ b/src/helpers/request-utils.ts
@@ -78,13 +78,17 @@ export const getRequestData = (request: Request): Partial<Request> => {
  * @returns data object
  */
 export const getFetchData = (args: [FetchResource, RequestInit]) => {
+    const requestClone = Request.prototype.clone;
     const fetchPropsObj: Record<string, unknown> = {};
 
     let fetchUrl: FetchResource;
     let fetchInit: RequestInit;
     if (args[0] instanceof Request) {
+        // Get real properties in case if data URL was used properties were set by Object.defineProperty
+        // https://github.com/AdguardTeam/Scriptlets/issues/367
+        const realData = requestClone.call(args[0]);
         // if Request passed to fetch, it will be in array
-        const requestData = getRequestData(args[0]);
+        const requestData = getRequestData(realData);
         fetchUrl = requestData.url as string;
         fetchInit = requestData;
     } else {
diff --git a/tests/scriptlets/trusted-replace-fetch-response.test.js b/tests/scriptlets/trusted-replace-fetch-response.test.js
index aa63427dd..084ea0c8c 100644
--- a/tests/scriptlets/trusted-replace-fetch-response.test.js
+++ b/tests/scriptlets/trusted-replace-fetch-response.test.js
@@ -253,4 +253,50 @@ if (!isSupported) {
         assert.strictEqual(url, urlExpected, 'response prop is copied');
         done();
     });
+
+    test('Data URL request, URL set by Object.defineProperty, content should NOT be replaced', async (assert) => {
+        const JSON_CONTENT = '{"adPlacements":true,"playerAds":true,}';
+        const BASE64 = btoa(JSON_CONTENT);
+        const DATA_REQUEST = `data:application/json;base64,${BASE64}`;
+        const REQUEST = new Request(DATA_REQUEST);
+        Object.defineProperty(REQUEST, 'url', {
+            get() {
+                return 'https://www.example.org/ad_url_test';
+            },
+        });
+        Object.defineProperty(REQUEST, 'method', {
+            get() {
+                return 'POST';
+            },
+        });
+        Object.defineProperty(REQUEST, 'bodyUsed', {
+            get() {
+                return !0;
+            },
+        });
+        Object.defineProperty(REQUEST, 'mode', {
+            get() {
+                return 'same-origin';
+            },
+        });
+        Object.defineProperty(REQUEST, 'body', {
+            get() {
+                return new ReadableStream();
+            },
+        });
+
+        const done = assert.async();
+
+        const PATTERN = 'adPlacements';
+        const REPLACEMENT = '';
+        const PROPS_TO_MATCH = 'ad_url_test';
+        runScriptlet(name, [PATTERN, REPLACEMENT, PROPS_TO_MATCH]);
+
+        const response = await fetch(REQUEST);
+        const actualTextContent = await response.text();
+
+        assert.strictEqual(window.hit, undefined, 'hit should NOT fire');
+        assert.strictEqual(actualTextContent, JSON_CONTENT, 'Content is intact');
+        done();
+    });
 }